10 Things to Know for Today

photo Apple workers gesture with five figners at customers leaving their store after purchasing iPhone 5 handsets in Covent Garden, London, Friday, Sept. 21, 2012. In a now familiar global ritual, Apple fans jammed shops Friday to pick up the tech juggernaut's latest iPhone. The smartphone is being launched in the U.S., Britain, Canada, France and Germany. It will go on sale in 22 more countries a week later.

Your daily look at late-breaking news, upcoming events and the stories that will be talked about today (times in EDT):

1. IPHONE HYSTERIA GOES GLOBAL

Some Apple fans have been camping out for days to get their hands on the iPhone 5.

2. ANTI-ISLAM FILM PROTEST TURNS DEADLY

Pakistani police open fire on rioters who were torching a cinema during a protest against "Innocence of Muslims," killing one man.

3. WHERE THE CANDIDATES ARE STUMPING

Obama speaks to the AARP at 11:30 a.m., and then attends a rally in Woodbridge, Va., at 12:45 p.m. Romney courts voters in Las Vegas at 5:05 p.m.

4. GOING WHERE NO RESEARCH HAS GONE BEFORE

AP's Marilynn Marchione says the nation's largest cancer center in Houston is launching a massive "moonshot" effort against eight specific forms of the disease.

5. ENDEAVORING TO DO WHAT TOURISTS DO

The space shuttle will spend its last flying day taking in California's Capitol, the Golden Gate Bridge and the Hollywood sign.

6. LAST 33,000 U.S. SURGE TROOPS LEAVE AFGHANISTAN

But deadly insider attacks and a reassessment of how NATO troops partner with Afghans raise questions about how well the military strategy is working.

7. ARENA MEANS REBIRTH IN BROOKLYN

After decades without a pro sports team, New York City's ascendant borough is entering the major leagues again - but this time it's basketball that's taking over.

8. NYC STRAPHANGERS WILL SEE ANTI-JIHAD ADS SOON

A conservative blogger wins a court order allowing her message equating some Muslim radicals with savages.

9. HOW THE TABBY GOT ITS DESIGN

Scientists identify the gene that sets the cat's common coat pattern - stripes or blotches.

10. FOR D.C. FANS, A LONG TIME COMING

Postseason baseball returns to the nation's capital for the first time since 1933 as the Washington Nationals clinch a playoff spot.

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