Lookout Mountain Judicial Circuit Drug Task Force agents found 8 pounds of crystal methamphetamine and 5 pounds of marijuana from a Rossville location, according to a news release Tuesday.
The release said agents obtained a search warrant during a follow-up investigation in the 500 block of James Street.
The drugs are valued at more than $400,000, according to the release.
Agents arrested Danyale Renee Cooper, 39, and Todd Lee Harmon, 39, who both live at the address.
No date or time was given for the raid and the arrests.
This story was updated Nov. 15 at 11:50 a.m.