DEAR DR. DONOHUE: I have been diagnosed with CPPD (pseudogout) in both knees. My treatment is colchicine, Mobic and Dilaudid. My right knee has become severely painful. My primary doctor said he is unaware of anything more to do other than increase the Dilaudid. It makes me groggy. Is there anything else I can do?

DEAR DR. DONOHUE: There’s something I don’t understand about muscles, body size and performance. I have seen very lean tennis players hit the ball 120 miles an hour while very beefy players hit it with a maximum speed of 70 miles an hour.

My brother was recently told he has ankylosing spondylitis.

DEAR DR. DONOHUE: About nine months ago I developed canker sores.

DEAR DR. DONOHUE: Will you explain what stage Parkinson’s disease starts with and how it progresses? My doctors have diagnosed me with it. Right now, I have shaking and my writing is bad. — A.M.

Will you comment on the treatment of blood clots in the legs?

DEAR DR. DONOHUE: Our 16-year-old grandson has come down with ulcerative colitis.

I need your help. I have had diarrhea for three months.

DEAR DR. DONOHUE: Please talk about lockjaw.

DEAR DR. DONOHUE: My mother has pernicious anemia.

I am a 43-year-old male who had never been sick until I had a kidney stone two months ago.

DEAR DR. DONOHUE: I am a new teacher and a new football coach at a high school in a small town that has no doctor.

DEAR DR. DONOHUE: I am a 70-year-old man who has developed breasts.

DEAR DR. DONOHUE: Our experience with my husband’s hiatal hernia was traumatic.

DEAR DR. DONOHUE: Three months ago, I had a cold and cough. The cold has gone, but the cough hasn’t.