Rite Aid at 4355 Mouse Creek Road in Cleveland, Tenn., was the site of an armed robbery about 8:05 p.m. Thursday.
Authorities said the suspect was described as a white male in his early 40s, dressed in a checkered blue shirt, blue jeans, blue hat and sunglasses.
The suspect fled the scene on foot, crossing the store parking lot.
Anyone with information is asked to phone Cleveland police at 423-476-7511.