Based on what is mentioned here it seems very likely that the missing person is dead. It is also very likely that the husband may have a connection with the death. Be sure to check for cleaning supplies (new/old and might be industrial strength). Also they need to be sure to check if anyone has been hired to clean the properties, or detail vehicles. Has anyone considered looking for her cell phone. Most modern cell phones have a gps, and can be activated remotely. There is a very good chance that there may be a residual charge in the battery of the phone. Cell towers can also be used to triangulate the last location of the cell phone, given that there was a call incoming or out going. It is unusual for a mentally well woman (assumed) to leave her children in a home by themselves, especially if she felt that the home environment may be dangerous. Were there any clothes missing? What about jewelry? How much gas was in the car? Any withdrawals, or activity on her card, or on the account that may seem unusual? Does the husband frequent any areas in particular? The husband made an agreement to allow the authorities to examine the house two months after the fact. That does seem unusual, especially if someone has nothing to hide. Is there any property, or location that the husband frequents/frequented? What about checking around the state lines for the missing vehicle.