AP photo by Phelan M. Ebenhack / Tennessee Titans running back Derrick Henry dives for a touchdown past Jacksonville Jaguars linebacker Dakota Allen (53) during the second half of Sunday's game in Jacksonville, Fla. Henry rushed for 130 yards on 29 carries, including three touchdowns.

JACKSONVILLE, Fla.— Derrick Henry enjoyed another happy homecoming while continuing to torment his hometown team.

Henry ran for 130 yards and three touchdowns about 25 miles from where he grew up, Kevin Byard returned a fumble for a score and the Tennessee Titans beat the Jacksonville Jaguars 37-19 in an AFC South Division game Sunday afternoon. It's the 20th loss in a row overall for the Jaguars, who are 0-5 in their first season under coach Urban Meyer.

Henry padded his NFL rushing lead — he has 640 yards on the ground through five games — as the Titans (3-2) rebounded from a stunning overtime road loss to the the New York Jets a week earlier and avoided consecutive defeats against winless teams.

"I think he's a stud," Titans left tackle Taylor Lewan said. "The crazy thing is, from a rushing standpoint, as an offensive line, we can do way better. We've played way better in the past. We're leaving a lot of meat on the bone there."

Henry ended a streak of three consecutive road games with at least 150 rushing yards, but he became the third player in franchise history to top 60 rushing touchdowns, joining Pro Football Hall of Famer Earl Campbell (73) and Eddie George (64). Henry has 62 in his career, including 14 against Jacksonville.

Henry and the Titans have won four straight and eight of nine in the series.

"Derrick does a great job pretty much every week," Titans quarterback Ryan Tannehill said. "You look at what he's done over the course of his career, especially the last three years. He's big, his physical and he's tough. He runs hard and he's durable. It's fun to be able to play with him."

Jacksonville moved into sole position of the second-longest skid in NFL history, six losses shy of tying the record the Tampa Bay Buccaneers set in 1976-77 over their first two seasons as an expansion team. The Jaguars' latest debacle came eight days after Meyer was captured on camera with a young woman dancing near his lap at an Ohio bar, behavior team owner Shad Khan called "inexcusable."

The coach was more animated than usual on the sideline and even ran near the goal line to celebrate a touchdown on a fourth-and-goal play, but Meyer ended up once again lamenting all that went wrong for his team.

"I see a group of warriors. I see a group of players that I love to death," said Meyer, whose success as a college coach included multiple national championships. "I see a group of players that are spilling it on the field, and we're not getting it. We're not closing it out."

The Jaguars fumbled on the third play of the game, and Byard scooped the ball up and ran 30 yards for a score. Jacksonville also: missed a PAT; dropped what should have been an interception (and maybe a pick-six); missed a 53-yard field-goal attempt; and was flagged for a phantom pass-interference penalty on third down.

Adding to the list, quarterback Trevor Lawrence appeared to run for his second score of the day in the fourth quarter, but replay officials ruled him down inside the 1-yard line, setting up a fourth-down call. Carlos Hyde was dropped for a 3-yard loss on the ensuing play, and center Brandon Linder sustained what appeared to be a significant leg injury.

The Titans probably needed all that fortune. Their defense was porous most of the afternoon, allowing 454 yards and forcing just two punts. Jacksonville's James Robinson ran 18 times for a career-high 149 yards and a touchdown.

"Not going to apologize for winning," Byard said. "Obviously, it wasn't pretty, it wasn't perfect at all. We've got to a lot of stuff we need to clean up. But happy to get a win, man, in Duval (County)."

Tennessee was better on the other side of the ball, with Yulee native Henry grinding out his yardage on 29 carries. Tannehill completed 14 of 22 passes for 197 yards with a touchdown.

The Jaguars will be designated the home team when they face the Miami Dolphins next Sunday in London.

The Titans have an extra day to prepare for their next game. The Buffalo Bills will visit Nashville on Oct. 18 for a Monday Night Football matchup.