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Friday, November 13, 2026Nov 13

Clemson-Louisville highlights trio of top 10 matchups

FILE - In this Sept. 22, 2016, file photo, Clemson quarterback Deshaun Watson (4) breaks into the open field as offensive lineman Jay Guillermo (57) blocks Georgia Tech defensive lineman Kyle Cerge-Henderson (54) during the first half of an NCAA college football game in Atlanta. Another Atlantic Division showdown, this time between No. 3 Louisville and No. 5 Clemson, plus a matchup of Wake Forest’s defense and NC State’s efficient offense and Syracuse’s chance to upset Notre Dame headline Week 5 in the Atlantic Coast Conference. (AP Photo/John Bazemore, File)
FILE - In this Sept. 22, 2016, file photo, Clemson quarterback Deshaun Watson (4) breaks into the open field as offensive lineman Jay Guillermo (57) blocks Georgia Tech defensive lineman Kyle Cerge-Henderson (54) during the first half of an NCAA college football game in Atlanta. Another Atlantic Division showdown, this time between No. 3 Louisville and No. 5 Clemson, plus a matchup of Wake Forest’s defense and NC State’s efficient offense and Syracuse’s chance to upset Notre Dame headline Week 5 in the Atlantic Coast Conference. (AP Photo/John Bazemore, File) FILE - In this Sept. 22, 2016, file photo, Clemson quarterback Deshaun Watson (4) breaks into the open field as offensive lineman Jay Guillermo (57) blocks Georgia Tech defensive lineman Kyle Cerge-Henderson (54) during the first half of an NCAA college football game in Atlanta. Another Atlantic Division showdown, this time between No. 3 Louisville and No. 5 Clemson, plus a matchup of Wake Forest’s defense and NC State’s efficient offense and Syracuse’s chance to upset Notre Dame headline Week 5 in the Atlantic Coast Conference. (AP Photo/John Bazemore, File)

The fifth week of the college football season offers arguably the best lineup of games since the opening weekend. With so many top 10 teams facing each other, this week could provide some clues on which teams have legitimate College Football Playoff aspirations.

BEST GAME

No. 3 Louisville at No. 5 Clemson.

This weekend features two other matchups of top 10 teams as No. 7 Stanford visits No. 10 Washington on Friday night and No. 8 Wisconsin plays at No. 4 Michigan on Saturday.

But the Atlantic Coast Conference showdown offers the most intrigue. The winner takes command of a loaded Atlantic Division that also features No. 12 Florida State, which already got blown out at Louisville two weeks ago.