Skip to main content
Sunday, November 15, 2026Nov 15

Tweaked COVID boosters close but how much will they help?

A Jackson, Miss., resident receives a Pfizer booster shot from a nurse at a vaccination site Tuesday, Feb. 8, 2022. In August 2022, Pfizer and Moderna both asked U.S. regulators to authorize modified versions of their booster vaccine — shots that are half the original recipe and half protection against BA.4 and BA.5, the newest subtypes of the coronavirus omicron variant. (AP Photo/Rogelio V. Solis, File)
A Jackson, Miss., resident receives a Pfizer booster shot from a nurse at a vaccination site Tuesday, Feb. 8, 2022. In August 2022, Pfizer and Moderna both asked U.S. regulators to authorize modified versions of their booster vaccine — shots that are half the original recipe and half protection against BA.4 and BA.5, the newest subtypes of the coronavirus omicron variant. (AP Photo/Rogelio V. Solis, File)

COVID-19 vaccines tweaked to better match today’s omicron threat are expected to roll out in a few weeks but still up in the air is how much benefit the booster shots will offer, who should get one — and how soon.

Pfizer and rival Moderna both asked U.S. regulators this week to authorize modified versions of their booster vaccine — shots that are half the original recipe and half protection against BA.4 and BA.5, the newest versions of omicron.

The Food and Drug Administration ordered that recipe and now is evaluating what scientists call a “bivalent vaccine,” with a decision expected soon.

Dr. Peter Marks, the FDA’s vaccine chief, said Thursday that once authorized, the tweaked boosters could help right away — while BA.5 infections still are too high — as well as hopefully blunt yet another winter surge.

Marks told the Associated Press that the new boosters could rev up the immune system to prevent not just serious illness but maybe milder infections, too, like the original vaccines did earlier in the pandemic, before super-contagious mutants emerged.