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Bills running back McCoy’s status uncertain against Giants

Buffalo Bills running back LeSean McCoy (25) celebrates his touchdown during the first half of an NFL football game against the Miami Dolphins, Sunday, Sept. 27, 2015 in Miami Gardens, Fla. To the right is Buffalo Bills wide receiver Percy Harvin (18) and wide receiver Robert Woods (10)(AP Photo/Lynne Sladky)
Buffalo Bills running back LeSean McCoy (25) celebrates his touchdown during the first half of an NFL football game against the Miami Dolphins, Sunday, Sept. 27, 2015 in Miami Gardens, Fla. To the right is Buffalo Bills wide receiver Percy Harvin (18) and wide receiver Robert Woods (10)(AP Photo/Lynne Sladky) Buffalo Bills running back LeSean McCoy (25) celebrates his touchdown during the first half of an NFL football game against the Miami Dolphins, Sunday, Sept. 27, 2015 in Miami Gardens, Fla. To the right is Buffalo Bills wide receiver Percy Harvin (18) and wide receiver Robert Woods (10)(AP Photo/Lynne Sladky)

ORCHARD PARK, N.Y. (AP) – Buffalo Bills coach Rex Ryan says there’s a “real possibility” running back LeSean McCoy will not play against the New York Giants on Sunday because of a nagging injury to his left hamstring.

Ryan said Wednesday before practice that “it doesn’t look good.” But he won’t entirely rule out McCoy from playing.

The injury has nagged and slowed McCoy since he was hurt during a joint practice with the Cleveland Browns on Aug. 18. McCoy sat out Buffalo’s final preseason games before playing a limited role in a season-opening win over Indianapolis on Sept. 13.

Following a 41-14 win at Miami on Sunday, both Ryan and McCoy acknowledged that rest might be the best option to give the injury time to heal.

The Bills (2-1) host the New York Giants (1-2) on Sunday.

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AP NFL website: www.pro32.ap.org and www.twitter.com/AP_NFL