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Tuesday, November 3, 2026Nov 3

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Two dead in wrong-way crash on Interstate 40 near Knoxville

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KNOXVILLE – Two people have died in a fiery wrong-way crash in Knoxville that closed lanes of Interstate 40.

Knoxville Police Department spokesman Darrell DeBusk told media the crash was reported about 1 a.m. Wednesday, just west of the Interstate 275 exchange. Initially, the interstate was closed in both directions, but westbound lanes reopened midmorning. Eastbound lanes remained closed.

DeBusk said a white SUV traveling west in the eastbound lanes collided head-on with a tractor-trailer. Both drivers were killed.

KPD Sgt. Nate Skellenger said he arrived at the scene to find the tractor-trailer engulfed in flames and wreckage strewn over interstate lanes in both directions.

Knoxville Fire Department Capt. D.J. Corcoran said the semi-truck was hauling a hazardous, flammable chemical, which was allowed to burn off. The scene was still being cleared as of late morning.