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APNewsBreak: Maria Sharapova pulls out of US Open

ADVANCE FOR WEEKEND EDITIONS, AUG. 29-30  - FILE - In this July 3, 2015, file photo, Maria Sharapova returns a ball to Irina-Camelia Begu during their singles match at the All England Lawn Tennis Championships in Wimbledon, London. Sharapova is seeded third for the U.S. Open tennis tournament. (AP Photo/Pavel Golovkin, File)
ADVANCE FOR WEEKEND EDITIONS, AUG. 29-30 - FILE - In this July 3, 2015, file photo, Maria Sharapova returns a ball to Irina-Camelia Begu during their singles match at the All England Lawn Tennis Championships in Wimbledon, London. Sharapova is seeded third for the U.S. Open tennis tournament. (AP Photo/Pavel Golovkin, File) ADVANCE FOR WEEKEND EDITIONS, AUG. 29-30 - FILE - In this July 3, 2015, file photo, Maria Sharapova returns a ball to Irina-Camelia Begu during their singles match at the All England Lawn Tennis Championships in Wimbledon, London. Sharapova is seeded third for the U.S. Open tennis tournament. (AP Photo/Pavel Golovkin, File)

The U.S. Tennis Association says Maria Sharapova is pulling out of the U.S. Open on the eve of the tournament because of a leg injury.

It’s the second time in three years that the 2006 champion has withdrawn from the year’s last Grand Slam event.

Sharapova has not played a match since losing to Serena Williams in the Wimbledon semifinals in July. She withdrew from hard-court tournaments in Toronto and Cincinnati in August, citing a right leg strain.

Sharapova is a five-time major champion who was seeded No. 2 for the U.S. Open, where play begins Monday.

The USTA says Sunday that Daria Kasatkina is the lucky loser who will replace Sharapova in the main draw.