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Thursday, October 29, 2026Oct 29

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A peek inside human brain shows a way it cleans out waste

This undated photo provided by the Oregon Health & Science University in October 2024 shows Drs. Erin Yamamoto, left, and Juan Piantino, who used special imaging to spot a long-suspected pathway the human brain uses to clear waste. (Christine Torres Hicks/OHSU via AP)
This undated photo provided by the Oregon Health & Science University in October 2024 shows Drs. Erin Yamamoto, left, and Juan Piantino, who used special imaging to spot a long-suspected pathway the human brain uses to clear waste. (Christine Torres Hicks/OHSU via AP) This undated photo provided by the Oregon Health & Science University in October 2024 shows Drs. Erin Yamamoto, left, and Juan Piantino, who used special imaging to spot a long-suspected pathway the human brain uses to clear waste. (Christine Torres Hicks/OHSU via AP)

WASHINGTON (AP) — A unique peek inside the human brain may help explain how it clears away waste like the kind that can build up and lead to Alzheimer’s disease.

Brain cells use a lot of nutrients which means they make a lot of waste. Scientists have long thought the brain has special plumbing to flush out cellular trash, especially during sleep – they could see it happening in mice. But there was only circumstantial evidence of a similar system in people.

Now researchers have finally spotted that network of tiny waste-clearing channels in the brains of living people, thanks to a special kind of imaging.

“I was skeptical,” said Dr. Juan Piantino of Oregon Health & Science University, whose team reported the findings Monday. “We needed this piece to say this happens in humans, too.”

The study was published in the journal Proceedings of the National Academy of Sciences.