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Jermaine Towns, left, and Brandon Shuford wait down the street from a multiple shooting at a nightclub in Orlando, Fla., Sunday, June 12, 2016. Towns said his brother was in the club at the time. A gunman opened fire at a nightclub in central Florida, and multiple people have been wounded, police said Sunday. (AP Photo/Phelan M. Ebenhack)

Read more about the Orlando massacre

ORLANDO, Fla. (AP) - The Latest on the shooting at an Orlando nightclub (all times local):

5:55 a.m.

Police say the person who opened fire inside a popular Florida nightclub is dead.

Orlando Police did not immediately provide further details on the department's official Twitter account on Sunday. It was not immediately clear how the shooter died. Police described the shooting as a "mass casualty situation" and said local, state and federal agencies were involved in the investigation.

It was not immediately clear how many people were wounded in the shooting, or if any of the victims had died. Police have told people to stay away from the area and said a noise in the vicinity was a "controlled explosion." No further details were provided on the explosion.

Dozens of emergency vehicles have swarmed the area around the club.

The club, Pulse Orlando, earlier posted on its own Facebook page just after 2 a.m.: "Everyone get out of pulse and keep running."

5:15 a.m.

Police say a loud noise near the scene of a reported shooting at a nightclub in Florida was a "controlled explosion."

Orlando Police said on the department's official Twitter account Sunday that media should avoid "reporting inaccuracies." No further details were immediately provided about the explosion.

Police have said "multiple injuries" were reported following the incident at the Pulse Orlando nightclub near Orange and Kaley avenue. The department also advised people to stay away from area.

Multiple emergency vehicles have reportedly responded, including the Orlando Fire Department's bomb squad and hazardous material team.

Pulse Orlando earlier posted on its own Facebook page just after 2 a.m.: "Everyone get out of pulse and keep running."

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4:50 a.m.

Orlando Police say they are responding to a shooting at a nightclub in Florida.

A post on the department's official Twitter account early Sunday morning says "multiple injuries" have been reported following the incident at the Pulse Orlando nightclub near Orange and Kaley avenue. The department also advises people to stay away from area.

Multiple emergency vehicles have reportedly responded, including the Orlando Fire Department's bomb squad and hazardous material team.

Pulse Orlando earlier posted on its own Facebook page: "Everyone get out of pulse and keep running."

The incident follows the fatal shooting on Friday of 22-year-old singer Christina Grimmie, who was killed after her concert in Orlando by a 27-year-old Florida man who later killed himself. Grimmie was a YouTube sensation and former contestant on "The Voice."

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